Creatine Kinase (CK)-MB-to-Total-CK Ratio: a Laboratory Indicator for Primary Cancer Screening
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چکیده
منابع مشابه
Standardization of creatine kinase-MB (CK-MB) mass assays: the use of recombinant CK-MB as a reference material.
BACKGROUND The AACC assembled a committee to identify and validate a standard creatine kinase MB isoenzyme (CK-MB) material to improve the comparability of CK-MB mass assays. METHODS Three protocols were used. In protocol I, various CK-MB materials prepared in different matrices were screened as candidate standards. In protocol II, participating manufacturers calibrated their systems with con...
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Three surveys of the measurement and interpretation of creatine kinase (CK; EC 2.7.3.2) isoenzyme 2 (CK-MB) were conducted in Ontario, Canada, in 1989. Of the clinical laboratories participating, 66% used immunological methods and 24% used electrophoretic methods. Although reference ranges and interpretative routines varied widely, 95% of the laboratories reported correct interpretations for 10...
متن کاملMacro-creatine kinase co-migrating with CK-MB on electrophoresis.
Certain types ofmacro-CK, type 1, have been reported to cause false increases in CK-MB by co-migration on electrophoresis (1-3). I report two such cases in which the macroCK was an IgA with anti-CK-BB specificity. According to methods proposed by Medeiros et al. (1), immunoprecipitation and subsequent analysis by elecrophoresis was used to separate interfering macre-CK from CK-MB. CK electropho...
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Özet– Alerjik semptomların miyokart iskemisi semptomlarına eşlik etmesi Kounis sendromu olarak tanımlanır. Etofenamat sık olarak kullanılan güvenli ve etkin bir steroid olmayan antienflamatuvar ilaçtır. Bu yazıda Kounis sendromlu 71 yaşında erkek hasta sunuldu. İntramüsküler 1 gram etofenamat enjeksiyonu sonrası eritamatöz döküntüler, kaşıntı, bulantı ve kusma, baş dönmesi, terleme ve göğüs ağr...
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Cytosolic brain-type creatine kinase (BB-CK), which is coexpressed with ubiquitous mitochondrial uMtCK, is significantly inactivated by oxidation, in Alzheimer's disease (AD) patients. Since CK has been shown to play a fundamental role in cellular energetics of the brain, any disturbance of this enzyme may exasperate the AD disease process. Mutations in amyloid precursor protein (APP) are assoc...
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Cancer Prevention
سال: 2015
ISSN: 1513-7368
DOI: 10.7314/apjcp.2015.16.15.6599